Recent studies demonstrate that genotype-guided antiplatelet strategies can reduce ischemic events in CYP2C19 loss of function allele carriers without increasing bleeding risk, while allowing safe de-escalation to clopidogrel in noncarriers. Join a multidisciplinary panel of experts to discuss the clinical challenges of DAPT in PCI, evidence for gene-guided therapy, and case-based strategies for implementing rapid genetic testing. At the end of this activity, participants will be able to: 1. Explain the impact of CYP2C19 genetic variants on clopidogrel efficacy and thrombotic risk. 2. Evaluate the risks of high versus low platelet reactivity and in individualized DAPT selection. 3. Appraise key clinical trials and current guideline and consensus recommendations for CYP2C19 testing in PCI. 4. Implement appropriate antiplatelet therapy de-escalation or escalation.
Credit & MOC Details
Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.
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FDA REMS
Qualifies for MIPS
Target Specialties
Pricing
CME included with membership
| Member | Free |
| Non-Member | $19 |
| Fellow-In-Training | Free |
| Cardio Team Member | Free |
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Pricing
Free
Reported to ACCME by the provider
- Case-based learning
- Credit · Up to 1 credit
- MOC · Up to 1 point
- Commercial Support
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ReleasedSep 15, 2026
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Last day to claim creditSep 16, 2029 3 years left
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The Ohio State University Anticoagulant and Antiplatelet Update
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Medscape, LLC Beyond the Cath Lab: IV Antiplatelet Therapy for High-Risk Scenarios
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Institute for Advanced Medical Education Balancing Risks and Benefits: Anticoagulation and Antiplatelet Therapy in Stroke Prevention in AFIB, Navigating Dual and Triple Therapies
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Society for Cardiovascular Angiography and Interventions, The From Clot Burden to Cardiogenic Shock: IV Antiplatelet Strategies in Acute MI Management
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Society for Cardiovascular Angiography and Interventions, The Conversation in Interventional Cardiology: Drug-Coated Balloons for De Novo Non aorto-ostial and Coronary Bifurcation Lesions: A Systematic Review and Meta-analysis
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Society for Cardiovascular Angiography and Interventions, The Technical Mastery: Guidance on Proper Imaging, Lesion Preparation, and Deployment for Coronary Drug-Coated Balloons. Part 2: Coronary DCBs in De Novo Lesions, Small Vessel, and Bifurcation: The European Experience
