In today's talk we will discuss the following topics: What are opiates, opioids, and narcotics? What are endogenous opioids? Opioid receptor classes. Opioid receptor distribution. Opioid receptor ligands, agonists, and antagonists. Opioid receptor structure. Opioid receptor signaling. References and attributions: Brunton, Laurence; Knollman, Bjorn; Hilal-Dandan, Randa. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition (Goodman and Gilman's the Pharmacological Basis of Therapeutics) (p. 1359). McGraw Hill LLC. Kindle Edition. Papaver Somniferum image: By tanja niggendijker from apeldoorn, the netherlands – poppiesUploaded by Epibase, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=8495875 GPCR | Learn Science at Scitable https://www.nature.com/scitable/topicpage/gpcr-14047471/ Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives – PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895212/ Untangling the complexity of opioid receptor function | Neuropsychopharmacology https://www.nature.com/articles/s41386-018-0225-3 Frontiers | Gi/o-Protein Coupled Receptors in the Aging Brain https://www.frontiersin.org/articles/10.3389/fnagi.2019.00089/full Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action | PNAS https://www.pnas.org/doi/10.1073/pnas.0508812103
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