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American Association for the Study of Liver Diseases

  • Liver Cirrhosis
  • Non-alcoholic Fatty Liver Disease
  • Semaglutide

Resmetirom and Semaglutide for MASH in 2025: Updated recommendations from AASLD Guidance

This session will address currently available treatment options for patients with non-cirrhotic MASH. Recent publications on real world use of resmetirom include high observed rates of prescription coverage but frequent AE s. Furthermore, early data on the use of resmetirom for 3 years in non-cirrhotic MASH and 2 years in patients with MASH cirrhosis are becoming available. Lastly, weekly semaglutide injections were approved by the FDA in September 2025 for non-cirrhotic MASH patients. In late 2025, the AASLD will publish an updated guidance on MASLD management that will be presented at the November Annual meeting. Therefore, there is an urgent need for members to become aware of the latest evidence based recommendations on what agents to select and how to optimally treat individual patients. In addition as the approved agents are used alone or in combination with other treatment strategies participants need to familiarize themselves with future options in this rapidly changing therapeutic landscape.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AMA PRA Category 1 Credit™Up to 1 credit

MOC types

ABIM — Medical KnowledgeUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Pricing

Free

Reported to ACCME by the provider

  • Blended / Other
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Released
    Dec 16, 2025
  • Last day to claim credit
    Dec 17, 2026 2 months left