Originally presented live at the 2026 Kentucky Overdose Prevention Summit (Louisville, KY). This keynote examines trends in the illicit drug supply and growing morbidity among people who inject drugs, drawing on epidemiologic data from law enforcement drug seizures and community-based drug checking programs. The presenter explores how an increasingly synthetic and toxic drug supply dominated by illicit fentanyl and novel adulterants is reshaping patterns of use and escalating overdose and infectious disease risk. Attendees gain an understanding of how drug market dynamics, including consumer preferences for specific substances and drug combinations, interact with harm reduction and treatment access. Upon completion of this activity, participants will be able to: 1. Learn how law enforcement drug seizures and community-based drug checking data can serve as proxy indicators for the illicit drug supply. 2. Understand the pharmacologic effects associated with an increasingly synthetic and toxic drug supply and their impact on public health and safety. 3. Recognize how the illicit drug market exerts influence on consumer preference for specific drugs, drug combinations, and modes of use, including the intent to be treated. Presented by: Jon Zibbell, PhD Senior Scientist, Center for Behavioral Health & Wellbeing, RTI International.
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Specialties served/covered
- Addiction Medicine
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- Comprehensive & Board Review
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- Hematology
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- Mood & Anxiety Disorders
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- Nephrology
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- Pediatric Hematology-Oncology
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