Tranexamic acid (TXA) is an antifibrinolytic medication with multiple routes of topical and systemic administration that can be used to treat acute hemorrhage across a broad range of clinical scenarios. Pediatric data are more limited than the adult literature, which benefits from larger, higher-quality studies; however, TXA remains a potentially effective, safe, and versatile option for temporizing bleeding and limiting blood loss in children. This review discusses the evidence on TXA use in traumatic hemorrhage, traumatic brain injury, posttonsillectomy bleeding, epistaxis, oral and gingival bleeding, lower airway bleeding, and traumatic hyphema.
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FDA REMS
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CME included with membership · $449–549/yr
| Single-Journal Annual Subscription | $449/yr |
| Two-Journal Annual Bundle | $499/yr |
| Three-Journal Annual Bundle | $549/yr |
| Single Issue Purchase | $99 |
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