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StatPearls, LLC

  • Cri-du-Chat Syndrome
  • In Situ Hybridization, Fluorescence
  • Prenatal Diagnosis

Cri Du Chat Syndrome

Cri du Chat syndrome is a rare chromosomal deletion disorder caused by partial or complete loss of the short arm of chromosome 5, producing a characteristic high-pitched cat-like cry in infancy along with craniofacial abnormalities, developmental delay, intellectual disability, and multisystem complications. This course reviews the clinical features of this disorder, which can vary in severity according to the size and location of the deletion, reflecting important genotype phenotype correlations that influence neurologic, behavioral, cardiovascular, feeding, and developmental manifestations. Advances in prenatal screening, cytogenetics, chromosomal microarray analysis, and fluorescence in situ hybridization are also discussed. Patients will also gain an understanding of management approaches that remain supportive and interprofessional, emphasizing early intervention, rehabilitation therapies, developmental support, medical surveillance, and genetic counseling. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying the genetic basis and clinical presentation of Cri du Chat syndrome, applying an appropriate diagnostic evaluation, understanding associated comorbidities, and implementing an appropriate interprofessional approach when managing this condition to optimize long-term outcomes, coordinate interprofessional care, and improve quality of life for affected individuals and their families.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABOHNS — Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 11 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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