Search 33,000+ CME courses
Back

StatPearls, LLC

  • Baclofen
  • Cerebral Palsy
  • Coma
  • Muscle Relaxants, Central
  • Seizures

Baclofen Toxicity

Baclofen is a centrally acting muscle relaxant used to manage spasticity associated with various neurologic conditions, including multiple sclerosis, cerebral palsy, and spinal cord injury. Baclofen toxicity may result from overdose, accumulation in renal impairment, or withdrawal of intrathecal therapy and can be life-threatening. Clinical manifestations range from somnolence, hypotonia, and respiratory depression to seizures, coma, and cardiovascular instability. Diagnosis is primarily clinical and supported by medication history. Management consists of supportive care, airway protection, seizure control, and hemodialysis in selected cases. Potential complications include aspiration, prolonged encephalopathy, rhabdomyolysis, and death. This activity for healthcare professionals is designed to sharpen learners’ skills in evaluating and managing baclofen toxicity. Participants will deepen their understanding of the relevant toxicokinetics, as well as the condition’s risk factors, pathophysiology, clinical presentation, and evidence-based diagnostic and therapeutic recommendations. Enhanced competence will equip clinicians to collaborate with interprofessional teams caring for individuals with baclofen poisoning.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1 creditAMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABPM — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABA — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABP — Lifelong Learning and Self-AssessmentUp to 1 pointABPM — Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 7 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

More from StatPearls, LLC

See all

This provider’s courses closest to this one

Related courses

See all

Other providers’ courses on the same topic