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StatPearls, LLC

  • Bisphosphonate-Associated Osteonecrosis of the Jaw
  • Diphosphonates
  • Multiple Myeloma
  • Osteonecrosis
  • Osteosclerosis

Bisphosphonate-Related Jaw Osteonecrosis

Bisphosphonates are synthetic pyrophosphate analogs used to treat hypercalcemia secondary to bone resorption conditions such as malignancy, osteoporosis, multiple myeloma, Paget disease, osteosclerosis, and fibrous dysplasia. Infrequent side effects associated with bisphosphonate use include pyrexia, renal function impairment, hypocalcemia, and, more recently recognized, avascular osteonecrosis of the jaw. According to the American Society of Bone and Mineral Research, bisphosphonate-related osteonecrosis of the jaw (BRONJ) is described as exposed bone in the maxillofacial region that does not heal within 8 weeks of being identified by a healthcare provider in a patient that is currently or has been on bisphosphonates who does not have a history of radiation therapy in the craniofacial region. This activity describes the evaluation and management of patients with bisphosphonate-related jaw osteonecrosis and highlights the role of the interprofessional team in improving care for affected patients.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsDentistryUp to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABOHNS — Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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