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StatPearls, LLC

  • Caroli Disease
  • Cholangiocarcinoma
  • Cholangiopancreatography, Magnetic Resonance
  • Cholangitis
  • Fibrosis

Caroli Disease

Caroli disease is a rare, congenital condition characterized by segmental dilation of large, intrahepatic bile ducts, which appear as cysts on imaging studies and histopathological examination. This condition is included in a group of congenital disorders known as fibropolycystic liver diseases, which originate from ductal plate malformations during embryological development. Patients with Caroli disease may frequently experience complications such as hepatolithiasis and recurrent cholangitis. Additionally, the patients are at increased risk for cholangiocarcinoma due to bile stasis and chronic inflammation. When Caroli disease is associated with congenital hepatic fibrosis, it is referred to as Caroli syndrome. Unlike Caroli disease alone, Caroli syndrome is characterized by sequela of hepatic fibrosis and portal hypertension. Recognizing Caroli disease and related conditions is crucial for effectively managing and preventing long-term complications. In Caroli disease, laboratory findings are often nonspecific, making imaging modalities such as ultrasonography, computed tomography, and magnetic resonance cholangiopancreatography essential for evaluation. Treatment is tailored to the clinical presentation and primarily involves supportive care. This activity reviews the pathophysiology, diagnosis, and treatment strategies for Caroli disease, emphasizing the condition’s diverse phenotypic spectrum. This activity also highlights the importance of collaboration within an interprofessional healthcare team to actively engage patients, improve clinical outcomes, and prevent long-term complications.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 7 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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