Cerebral folate deficiency (CFD), a condition characterized by low cerebrospinal fluid folate despite normal serum levels, is a significant and poorly understood contributor to neuropsychiatric symptoms such as, anxiety, depression, cognitive decline, memory loss, and OCD. Although underrecognized in the context of infection-triggered illness, CFD may play a key role in the neurological and psychiatric manifestations seen in this population. This presentation will explore the pathophysiology and clinical manifestations of CFD, highlight challenges in diagnosis, and present the theoretical overlap between CFD and neuropsychiatric symptoms. Practical clinical strategies will also be discussed, including testing for folate receptor autoantibodies and genomic SNPs, the role of dairy elimination, and the therapeutic use of high-dose folinic acid, offering hope for symptom relief in patients with neuropsychiatric symptoms.
Credit & MOC Details
Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.
Credit types
MOC types
FDA REMS
Qualifies for MIPS
Target Specialties
Address:
- 104 Windsor Center Drive
Pricing
CME included with membership · $99–598/yr
| New Membership – Standard | $349/yr |
| New Membership – Standard (2-year) | $598/yr |
| New Membership – Military/VA | $259/yr |
| New Membership – Student/Resident | $149/yr |
| Renewal Membership – Standard | $249/yr |
| Renewal Membership – Standard (2-year) | $478/yr |
+27 more tiers
Collected from the provider’s public pages · source
Specialties served/covered
- Child & Adolescent Psychiatry
- Clinical Informatics
- Communication & Shared Decision-Making
- General & Adult Psychiatry
- General Surgery
- Interventional Radiology
- Mood & Anxiety Disorders
- Neurology
- Neuroradiology
- Nuclear Medicine
- Pain Medicine
- Pediatric Neurology
- Practice Management & Ethics
- Psychopharmacology
- Psychotic Disorders
- Sleep Medicine
- Cross-Specialty
- Medical Subspecialties
- Neurology
- Pain & Palliative
- Psychiatry
- Radiology
- Surgery
- No reviews yet. Be the first to share yours.
- On-demand / recorded video
- Credit · Up to 1 credit
- MOC · Up to 1 point
- $19
-
ReleasedMar 11, 2026
-
Last day to claim creditMar 12, 2027 5 months left
-
Carlat CME Institute Folate and Depression, April 28, 2025
-
Carlat CME Institute Folate, Valproate, and Lamotrigine, April 21, 2025
-
National Ovarian Cancer Coalition +1 Powering Pathology Precision: Expert Strategies for Folate Receptor Alpha Testing to Guide Personalized ADC Care in Advanced Ovarian Cancer
-
Psychiatry Redefined, HMP Education Autism, Increased Oxidative Stress, and Impaired Methylation Capacity What Every Health Practitioner Should Know
-
Psychiatry Redefined, HMP Education The Gut-Brain Masquerade: How Pediatric Gastrointestinal Disorders Can Mimic, Amplify, and Sustain Psychiatric Symptoms
-
Psychiatry Redefined, HMP Education Mind The Gut: How Yeast & Other Dysbiosis Can Impact Behavior & Neuropsychiatric Symptoms
