Back

StatPearls, LLC

  • Atrophy
  • Chronic Traumatic Encephalopathy
  • Cognitive Dysfunction
  • Organ Transplantation
  • Tauopathies

Chronic Traumatic Encephalopathy

Chronic traumatic encephalopathy (CTE), formerly known as repetitive head injury syndrome, is a progressive neurodegenerative disorder commonly observed in individuals involved in contact sports or military service. This condition is characterized by specific brain abnormalities, including regional atrophy, ventriculomegaly, and the deposition of neurofibrillary tangles and neuropil threads, contributing to a distinct form of tauopathy. Although CTE can only be definitively diagnosed postmortem, recent consensus guidelines provide criteria for identifying its clinical manifestations, referred to as traumatic encephalopathy syndrome. The clinical presentation of CTE varies, with younger individuals often exhibiting mood and behavioral symptoms, while older patients may experience cognitive impairments. The disease progresses through stages, eventually leading to severe cognitive dysfunction and neurodegeneration. CTE currently has no cure, and treatment primarily focuses on managing symptoms. Research highlights the need for prospective, longitudinal studies incorporating fluid and imaging biomarkers to improve the understanding and management of the condition. This activity comprehensively reviews chronic transplant rejection, covering its characteristics, historical background, diagnostic criteria, and postmortem diagnosis. This activity also delves into recent advancements in imaging techniques and potential fluid biomarkers alongside current management approaches and preventive strategies. In addition, this activity enhances healthcare providers’ knowledge and skills in effective management and prevention strategies for chronic transplant rejection, emphasizing interprofessional collaboration to improve patient outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABPMR — Accredited CMEUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABPMR — Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left