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StatPearls, LLC

  • Chronic Pain
  • Ehlers-Danlos Syndrome
  • Genetic Testing
  • Joint Instability
  • Rupture

Ehlers-Danlos Syndromes

Ehlers-Danlos syndromes (EDS) comprise a diverse group of heritable connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility with multisystem involvement that often leads to delayed recognition and diagnosis. This course discusses advances in classification and molecular genetics that have expanded understanding of the 14 recognized EDS subtypes, including the severe vascular form associated with arterial and organ rupture. This activity reviews the clinical manifestations of EDS that range from chronic pain, recurrent dislocations, autonomic dysfunction, and poor wound healing to life-threatening vascular and obstetric complications, as well as its diagnostic evaluation, including recognition of characteristic clinical findings, targeted genetic testing for most subtypes, and careful differentiation from other connective tissue disorders. Participants will gain an understanding of EDS pathophysiology, subtype classification, genetic evaluation, surveillance strategies, and evidence-based management approaches. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying EDS, performing the recommended evaluation, and implementing an appropriate interprofessional approach when managing this condition to improve long-term patient outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 2 creditsAMA PRA Category 1 Credit™Up to 2 creditsNursingUp to 2 creditsPharmacyUp to 2 credits

MOC types

ABS — Accredited CMEUp to 2 pointsABOS — Accredited CMEUp to 2 pointsABPATH — Lifelong LearningUp to 2 pointsABA — Lifelong LearningUp to 2 pointsABPMR — Accredited CMEUp to 2 pointsABTS — Accredited CMEUp to 2 pointsABIM — Medical KnowledgeUp to 2 pointsABS — Self-AssessmentUp to 2 pointsABP — Lifelong Learning and Self-AssessmentUp to 2 pointsABOHNS — Self-AssessmentUp to 2 pointsABPMR — Self-AssessmentUp to 2 pointsABTS — Self-AssessmentUp to 2 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 13 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 2 credits
  • MOC · Up to 2 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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