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StatPearls, LLC

  • Neoplasm Metastasis
  • Sarcoma

Epithelioid Sarcoma

Epithelioid sarcoma is a rare and aggressive soft tissue sarcoma characterized by both epithelial and mesenchymal differentiation. This condition most commonly affects young adults and typically presents as a painless and slow-growing mass, which is often located in the distal extremities. Despite its slow growth, epithelioid sarcoma is highly aggressive, posing a significant risk of recurrence, lymph node involvement, and distant metastases. Diagnosis is typically made through tissue biopsy, while imaging studies are essential for assessing the extent of the primary tumor and identifying metastatic disease. Microscopically, the conventional form exhibits a nodular or lobular architecture with central necrosis and surrounding epithelioid cells, while the proximal-type variant is characterized by more cytologic pleomorphism and nuclear atypia. The primary treatment for epithelioid sarcoma is complete surgical removal, which is curative in the early stages. Radiation therapy may be used as an adjunct to reduce recurrence risk, and more recently, targeted therapies have been developed for advanced cases. Due to the high likelihood of late metastases, long-term monitoring is essential for managing the disease. This activity reviews the etiology, histopathology, evaluation, and management of epithelioid sarcoma. This activity also helps healthcare providers identify, diagnose, and manage epithelioid sarcoma, ensuring timely and accurate treatment and improving patient outcomes through early interprofessional collaboration.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABOS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABPMR — Accredited CMEUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABPMR — Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 6 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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