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StatPearls, LLC

  • Bilirubin
  • Dehydration
  • Fasting
  • Gilbert Disease
  • Hyperbilirubinemia

Gilbert Syndrome

Gilbert syndrome is a common genetic disorder affecting bilirubin metabolism in the liver. This autosomal recessive condition leads to mild to moderate unconjugated hyperbilirubinemia, often presenting as recurrent episodes of jaundice. The prognosis for individuals with Gilbert syndrome is excellent, and the condition does not lead to significant liver disease. However, patients with Gilbert syndrome may have an increased risk of drug toxicity when exposed to medications that affect bilirubin metabolism. Patients with Gilbert syndrome typically have normal liver function tests aside from elevated unconjugated bilirubin levels. The condition is generally asymptomatic and does not require treatment, but several factors, including fasting, illness, menstruation, and dehydration, may trigger symptoms. Diagnosing Gilbert syndrome involves excluding other causes of hyperbilirubinemia. This activity for healthcare professionals reviews the etiology, epidemiology, pathophysiology, clinical presentation, recommended evaluation, and management of Gilbert syndrome and highlights the role of the interprofessional team in improving the quality of life and outcomes for patients with this genetic disorder.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1 creditAMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABP — Lifelong Learning and Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 6 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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