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StatPearls, LLC

  • Acute Kidney Injury
  • Hemolytic-Uremic Syndrome
  • Shiga Toxins

Hemolytic Uremic Syndrome

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. The disorder is most commonly caused by Shiga toxin producing bacterial infections (typical HUS) but may also result from dysregulation of the alternative complement pathway, infections, medications, autoimmune diseases, malignancies, or genetic abnormalities (atypical HUS). Clinical manifestations range from mild hematologic abnormalities to severe renal, neurologic, and gastrointestinal complications. Because HUS shares clinical features with other thrombotic microangiopathies, prompt recognition of the underlying cause is essential, as management strategies differ significantly. Treatment of typical HUS is primarily supportive, whereas complement inhibition has dramatically improved outcomes in atypical HUS. Early diagnosis and appropriate management are critical to reducing morbidity and mortality and improving long-term renal and neurologic outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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