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StatPearls, LLC

  • Coinfection
  • Hepatitis B
  • Hepatitis D
  • Liver Cirrhosis
  • Superinfection

Hepatitis D

Hepatitis D virus (HDV) is a unique pathogen that requires the presence of hepatitis B virus (HBV) for its replication and spread. HDV uses the HBV surface antigen as its envelope protein, making it dependent on the coinfection or superinfection with HBV to cause disease. Clinically, HDV infection can lead to more severe liver disease than HBV alone. In acute HBV-HDV superinfection, patients may experience a biphasic course with 2 distinct peaks in serum alanine aminotransferase, reflecting the sequential spread of HBV and HDV. Chronic infection with both viruses can result in faster progression to cirrhosis and liver failure. HDV also has the unique characteristic of suppressing HBV replication, although the mechanism remains unknown. Timely serological testing is crucial for identifying HDV infection in patients with HBV, as this coinfection requires specific management approaches. Participants in this course gain a comprehensive understanding of HDV, including its dependence on HBV for transmission, the clinical presentation of coinfection, and the associated complications. They learn how to evaluate patients with suspected HDV by conducting appropriate serological tests and recognize the importance of early diagnosis in improving outcomes. The course emphasizes the role of an interprofessional healthcare team, including hepatologists, infectious disease specialists, and nurses, in providing holistic care. Collaborating with this team enhances patient outcomes by ensuring that the complexities of managing HBV-HDV coinfection are addressed through coordinated efforts, tailored treatment plans, and comprehensive monitoring strategies.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • includes Online course / module
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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