StatPearls, LLC

  • Dopamine Agonists
  • Galactorrhea
  • Headache
  • Hyperprolactinemia
  • Prolactinoma

Hyperprolactinemia

Prolactin, a hormone exclusively synthesized and secreted by lactotrophs in the anterior pituitary gland, plays a vital role in reproductive physiology. Hyperprolactinemia, defined by serum prolactin levels exceeding 15 to 20 ng/mL, may arise from physiological, pathological, or drug-induced causes. This course reviews the clinical presentation of hyperprolactinemia, including reproductive dysfunction, galactorrhea, or symptoms of mass effect such as headache and visual field defects. Participants will gain an understanding of the evaluation, which involves serum prolactin measurement, exclusion of secondary causes, and pituitary imaging, as well as key diagnostic considerations, including the hook effect and macroprolactinemia. This course explores prolactin physiology, hyperprolactinemia evaluation, and evidence-based management, which depends on etiology and may involve thyroid replacement, medication adjustments, or dopamine agonists. Surgery or radiotherapy is reserved for resistant prolactinomas. The interpretation of laboratory and imaging findings, identification of diagnostic pitfalls, and application of appropriate therapeutic strategies are also discussed. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying hyperprolactinemia, performing the recommended evaluation, and implementing an appropriate interprofessional approach when managing this condition, ultimately optimizing outcomes for patients with prolactin disorders and patient-centered endocrine care.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 13 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left