Incredible Incretins: Applying the Evidence Behind GIPs and GLP-1s

Given the wide-ranging benefits seen with incretin-based therapies, modulating the release of endogenous gut hormones, such as GIP and GLP-1, through dietary modification may be a promising approach for the treatment of obesity and type 2 diabetes, especially when combined with synthetic incretin analogues (GLP-1RAs). Furthermore, the use of endogenous incretins has the advantage of mitigating the known GLP-1 medication side effects, as well as stimulating the release of other appetite suppressing hormones. However, a current understanding of the cellular mechanisms underlying intestinal hormone secretion is critical. Incretins have been shown to influence the reward center of the brain and mitigate the desire to consume food simply for pleasure (hedonic response). Thus, an understanding of the biology of homeostatic and non-homeostatic weight loss is necessary. Knowledge of the latest clinical trial data, new GLP-1 s on the market as well as those in the pipeline, patient selection criteria, dosing guidelines and more is essential when care team members are counseling patients on the use of incretin therapy for weight loss and metabolic disease management. Join Om Ganda, MD, MACE, and Sangeeta Pradhan, M.Ed, RD, LDN, CDCES, for a webinar that will discuss the efficacy of incretin-based therapies, the long-term outlook including several unanswered questions, and explore the indispensable role diet plays in enhancing endogenous GLP-1 production. Care team members will gain a comprehensive toolkit that will help them collaborate and integrate carefully selected diets and incretin-based therapies. By working together and understanding the science, practitioners will be able to support patients who seek a more sustainable, longer lasting, and more efficacious outcome when managing weight, blood glucose levels, metabolic disorders, and other clinical endpoints.

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Nov 13, 2025
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Nov 5, 2028 2 years left

Incredible Incretins: Applying the Evidence Behind GIPs and GLP-1s

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