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StatPearls, LLC

  • Electroencephalography
  • Genetic Testing
  • Lennox Gastaut Syndrome
  • Long-Term Care
  • Seizures

Lennox-Gastaut Syndrome

Lennox-Gastaut Syndrome (LGS) is a lifelong, developmental epileptic encephalopathy that typically begins before age 8, with peak onset between the ages of 3 and 5. LGS is characterized by frequent seizures, including atonic, tonic, and atypical absence seizures, which contribute to behavioral disorders and intellectual disabilities. Multiple seizures are often accompanied by distinctive electroencephalogram (EEG) patterns, including interictal slow spike-wave discharges and generalized paroxysmal fast activity during sleep. Although many cases of LGS are linked to underlying genetic mutations or cortical malformations, up to 40% have no identifiable cause. Diagnosis relies on clinical presentation, EEG findings, brain magnetic resonance imaging, and genetic testing. Due to the complexity of the condition and its long-term care requirements, LGS significantly impacts patients’ quality of life, placing considerable strain on caregivers and healthcare systems. Seizures are often treatment-resistant, necessitating multimodal therapy and coordinated, multidisciplinary care. This activity reviews the clinical presentation, underlying causes, and complex management of LGS. This activity provides healthcare professionals with the knowledge to recognize hallmark seizure types and EEG patterns, differentiate LGS from other pediatric epilepsies, and apply diagnostic strategies, including neuroimaging and genetic testing. Additionally, this activity covers evidence-based approaches to both pharmacological and surgical seizure management, preparing healthcare providers to address the challenges of treatment resistance. This activity also emphasizes the importance of interprofessional collaboration among the healthcare team in coordinating multidisciplinary care and delivering patient and caregiver education, ultimately supporting improved outcomes and quality of life for individuals living with LGS.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 8 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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