Biopsy, Large-Core Needle
Liposarcoma
Prognosis

Liposarcoma

Liposarcoma is the most common soft-tissue sarcoma in adults, accounting for approximately 20% of cases and arising most often in the extremities and retroperitoneum. This course outlines the 4 histologic subtypes recognized by the World Health Organization well-differentiated, dedifferentiated, myxoid, and pleomorphic and their characteristic features, as each is defined by distinct molecular alterations, clinical behavior, and treatment response. The recommended diagnostic evaluation for liposarcomas, which relies on cross-sectional imaging and image-guided core needle biopsy, is also discussed. This activity reviews liposarcoma pathogenesis, clinical presentation, interpretation of diagnostic evaluation findings, prognosis, and management strategies, including complete surgical resection with negative margins and radiation and systemic treatments selected based on tumor grade, location, and subtype. Participants will also gain an understanding of appropriate imaging selection, biopsy techniques, molecular diagnostics, staging, and interprofessional treatment planning. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying liposarcomas, recognizing red-flag symptoms, understanding subtype-specific therapeutic considerations, determining prognostic factors to support accurate diagnosis, ensuring timely referral, optimizing patient-centered care across clinical settings, and implementing an appropriate interprofessional approach when managing this condition.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.