Endometrial Hyperplasia
Endometrial Neoplasms
Gonadotropin-Releasing Hormone
Medroxyprogesterone
Progestins

Medroxyprogesterone

Medroxyprogesterone is used to prevent pregnancy in females of reproductive potential and for women experiencing amenorrhea due to hormonal imbalance, excluding organic pathologies such as fibroids and uterine cancer. Additionally, medroxyprogesterone is used for abnormal uterine bleeding due to ovulatory dysfunction, prevention of endometrial hyperplasia, pain related to endometriosis, and in patients with inoperable, recurrent, and/or metastatic endometrial carcinoma as adjunctive and/or palliative treatment. Medroxyprogesterone, a progestin, is similar in structure to naturally occurring progesterone. The mechanism of action of progestin involves binding the progesterone receptor in the hypothalamus, female reproductive tract, and pituitary and inhibiting the secretion of gonadotropin-releasing hormone (GnRH). This activity highlights medroxyprogesterone as contraception to prevent pregnancy and discusses the mechanism of action, adverse effects, monitoring, and contraindications for medroxyprogesterone, as well as the importance of regularly monitoring patients for adverse effects. An interprofessional team comprising primary care, ob/gyn, or related specialties might provide the best recommendations.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.