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StatPearls, LLC

  • Amenorrhea
  • Pregnancy Tests
  • Puberty, Delayed

Primary Amenorrhea

Amenorrhea is generally defined as the absence of menstruation in a female of reproductive age. It can be classified as either primary or secondary amenorrhea. Primary amenorrhea is the failure to reach menarche (ie, the first menstrual cycle) during normal development. It is clinically diagnosed when there is no history of menstruation by the age of 15 years or 3 years after menarche. Patients meeting the criteria for primary amenorrhea warrant an evaluation. Additionally, an assessment for delayed puberty is indicated in adolescents aged 13 years and younger without initial breast development or other secondary sex characteristics (eg, pubic and axillary hair). Most of the underlying causes of primary amenorrhea can be classified into general groups: anatomic and sexual development abnormalities, ovarian insufficiency, hypothalamic or pituitary disorders, and other endocrine gland disorders. Physiology and medications may also cause primary amenorrhea; however, they are more commonly associated with secondary amenorrhea. The initial work-up usually includes a comprehensive history and physical examination, a urine pregnancy test, serum hormone testing, and pelvic imaging. Additional testing may also be indicated based on the clinical presentation. Treatment depends on the underlying etiology and may include lifestyle interventions, hormone therapy or other medications, surgery, and mental health services. Therefore, this activity for healthcare professionals is designed to enhance the learner’s competence when managing primary amenorrhea, equipping them with updated knowledge, skills, and strategies for timely diagnosis, effective interventions, and improved care coordination, leading to better patient outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 2 creditsAAPA Category 1 Credit™Up to 2 creditsAMA PRA Category 1 Credit™Up to 2 creditsNursingUp to 2 creditsPharmacyUp to 2 credits

MOC types

ABS — Accredited CMEUp to 2 pointsABPATH — Lifelong LearningUp to 2 pointsABTS — Accredited CMEUp to 2 pointsABIM — Medical KnowledgeUp to 2 pointsABS — Self-AssessmentUp to 2 pointsABP — Lifelong Learning and Self-AssessmentUp to 2 pointsABTS — Self-AssessmentUp to 2 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 7 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 2 credits
  • MOC · Up to 2 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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