Blepharochalasis syndrome, a rare disease of unknown etiology, typically manifests during childhood or adolescence through episodes of autonomously resolving eyelid edema. An active stage, characterized by recurrent upper eyelid swelling, is followed by a quiescent stage marked by sequelae without inflammatory signs. Recurrent, painless, nonpitting edema of the upper eyelids can induce gradual atrophy and laxity of the periorbital tissues in certain individuals. Although visual function remains unaffected, repeated episodes of inflammation often lead to periocular complications that require surgical intervention after the active stage ceases. The condition is diagnosed through clinical assessment supported by a pattern of recurrent eyelid edema followed by tissue laxity. Management typically involves conservative observation during the active phase, with surgical correction considered once the episodes have resolved. This activity enables healthcare professionals to improve their ability to evaluate, diagnose, and manage blepharochalasis syndrome. Participants gain knowledge of the condition s risk factors, clinical trajectory, and treatment strategies, including when surgical intervention is appropriate. Collaborative engagement with an interprofessional team such as ophthalmologists, dermatologists, and surgeons fosters timely diagnosis, comprehensive care planning, and improved cosmetic and functional outcomes for affected individuals.
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