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StatPearls, LLC

  • Anaphylaxis
  • Diphenhydramine
  • Nausea
  • Rhinitis, Allergic
  • Vomiting

Diphenhydramine Toxicity

Diphenhydramine is most often used for the treatment of nausea, vomiting, allergic rhinitis, mild to severe allergic reactions (e.g., anaphylaxis), and as a mild sleep aid. However, due to easy access to this medication, it is often abused and can lead to acute intoxication. To avoid the potentially serious complications and mortality associated with diphenhydramine toxicity, it must be promptly diagnosed and treated. This activity describes the evaluation and management of diphenhydramine toxicity and highlights the role of the interprofessional team in managing patients with this condition.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1 creditAAPA Category 1 Credit™Up to 1 creditAMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABPM — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABA — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABP — Lifelong Learning and Self-AssessmentUp to 1 pointABPM — Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 9 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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