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StatPearls, LLC

  • Cicatrix
  • Epidermolysis Bullosa

Epidermolysis Bullosa

Epidermolysis bullosa (EB) defines a group of rare, inherited dermatoses that present with repeated blistering, erosions, and ulceration in response to seemingly disproportionate mechanical trauma. This occurs due to genetically-mediated skin fragility defects within the dermo-epidermal junction. An extensive phenotypic range is described. Some forms of epidermolysis bullosa place patients at an increased risk of infection, disabling deformities secondary to heavy scarring, and aggressive cutaneous malignancy, often causing early fatality. A broad range of extra-cutaneous manifestations can lead to significant morbidity and premature mortality. In the absence of curative treatment, the current focus of care prioritizes preventing and relieving symptoms and their complications. More recently, novel therapeutics, including topical gene therapies, have gained approval for increased symptomatic improvement of this otherwise intractable group of conditions. This activity outlines the presentation, pathophysiology, evaluation, and management of epidermolysis bullosa, and describes the vital role of the interdisciplinary team in treating extra-cutaneous complications. Areas of research are highlighted pertaining to preventative and abortive clinical strategies, emphasizing the use of gene replacement therapy.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABOS — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABA — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABP — Lifelong Learning and Self-AssessmentUp to 1 pointABOHNS — Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 13 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Dec 1, 2024
  • Last day to claim credit
    Dec 1, 2026 7 weeks left

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