StatPearls, LLC

  • Acidosis
  • Ethanol
  • Fomepizole
  • Palliative Care
  • Taste

Ethylene Glycol Toxicity

Ethylene glycol is a toxic alcohol commonly found in antifreeze and some industrial solvents. Because this compound is a colorless liquid with a sweet taste, it contributes to accidental ingestions, particularly in children, and intentional ingestions in cases of end-of-life attempts or inebriation. Toxicity primarily arises from ingestion, as dermal absorption is minimal. Ethylene glycol metabolism produces toxic metabolites that can cause significant morbidity and mortality if left untreated. Timely recognition and management, including supportive care, laboratory monitoring, and antidotal therapies such as fomepizole or ethanol, are critical for patient outcomes. Participants in this course gain a comprehensive understanding of the pathophysiology, clinical progression, and management of ethylene glycol toxicity. They learn to identify risk factors, differentiate ethylene glycol toxicity from other causes of metabolic acidosis, and implement evidence-based diagnostic and treatment protocols. Skills include interpreting laboratory findings, initiating antidotal therapy, and recognizing indications for hemodialysis. Collaborative care with toxicologists, nephrologists, and critical care specialists is emphasized to optimize patient outcomes. Participants also explore strategies to prevent accidental exposures and counsel patients and families effectively. Enhanced competence ensures improved recognition, timely intervention, and reduced morbidity and mortality associated with ethylene glycol toxicity.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 2 creditsAMA PRA Category 1 Credit™Up to 2 creditsNursingUp to 2 creditsPharmacyUp to 2 credits

MOC types

ABS — Accredited CMEUp to 2 pointsABPM — Accredited CMEUp to 2 pointsABPATH — Lifelong LearningUp to 2 pointsABA — Lifelong LearningUp to 2 pointsABTS — Accredited CMEUp to 2 pointsABIM — Medical KnowledgeUp to 2 pointsABS — Self-AssessmentUp to 2 pointsABP — Lifelong Learning and Self-AssessmentUp to 2 pointsABPM — Self-AssessmentUp to 2 pointsABTS — Self-AssessmentUp to 2 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 8 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • includes Online course / module
  • Credit · Up to 2 credits
  • MOC · Up to 2 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left