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StatPearls, LLC

  • Dyslipidemias
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypercholesterolemia
  • Hypertriglyceridemia
  • Hypolipidemic Agents

Fibric Acid Antilipemic Agents

Fibric acid derivatives, or fibrates, are lipid-lowering agents approved for treating primary hypercholesterolemia and mixed dyslipidemia. As agonists of peroxisome proliferator-activated receptor alpha, fibrates reduce triglycerides and modestly increase high-density lipoprotein cholesterol, offering therapeutic benefits in patients with severe hypertriglyceridemia or atherogenic dyslipidemia. Despite their utility, fibrates are underprescribed due to concerns over potential adverse effects particularly myopathy when used with statins and limited clinician familiarity with patient selection, drug monitoring, and the United States Food and Drug Administration-labeled versus off-label indications. Fibrates are recommended in conjunction with dietary and lifestyle modifications and are used in clinical scenarios ranging from cardiovascular risk management to triglyceride-induced pancreatitis prevention. This educational activity enhances clinician competence in identifying appropriate candidates for fibrate therapy, applying evidence-based treatment protocols, and managing drug interactions and monitoring requirements. Clinicians gain practical tools to balance benefits and risks, especially when combining fibrates with other lipid-lowering agents. Interprofessional collaboration among physicians, pharmacists, nurses, and dietitians improves medication safety, reinforces adherence to dietary interventions, and ensures timely monitoring. Team-based care contributes to optimized lipid control, reduced treatment complications, and improved cardiovascular outcomes in high-risk patient populations.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 8 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left