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StatPearls, LLC

  • Acidosis
  • Delayed Diagnosis
  • Fructose
  • Fructose Intolerance
  • Hypoglycemia

Fructose-1-Phosphate Aldolase Deficiency

This continuing education activity reviews hereditary fructose intolerance, a rare autosomal recessive metabolic disorder caused by aldolase B deficiency that can lead to recurrent hypoglycemia, metabolic acidosis, hepatic dysfunction, renal injury, and failure to thrive after fructose exposure. Because early manifestations are nonspecific and often emerge during infancy when fructose-containing foods are introduced, clinicians may not promptly recognize the disorder or initiate appropriate evaluation. This gap can result in delayed diagnosis, preventable metabolic crises, and avoidable end-organ complications. The activity addresses this gap by strengthening clinical recognition, diagnostic reasoning, genetic confirmation, dietary management, complication surveillance, family counseling, and interprofessional coordination. Participants will gain practical strategies for identifying suspected hereditary fructose intolerance, avoiding unsafe fructose exposure, supporting lifelong dietary adherence, monitoring hepatic and renal outcomes, and improving patient-centered long-term care.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1 creditAAPA Category 1 Credit™Up to 1 creditAMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABP — Lifelong Learning and Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 7 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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