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StatPearls, LLC

  • Antimalarials
  • Glucosephosphate Dehydrogenase Deficiency
  • Hemolysis
  • Hyperbilirubinemia, Neonatal
  • Kernicterus

Glucose-6-Phosphate Dehydrogenase Deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymatic disorder affecting cellular defense against oxidative stress. Because erythrocytes lack nuclei and repair mechanisms, a deficiency in G6PD can lead to acute hemolytic anemia during oxidative challenges such as infections, ingestion of fava beans, or exposure to certain drugs, including antimalarials and sulfonamides. The condition may also contribute to neonatal hyperbilirubinemia and kernicterus, particularly when diagnosis or management is delayed. This course reviews the accurate recognition, diagnostic testing, and preventive counseling for G6PD, which are essential for reducing morbidity and improving patient safety. This course explores G6PD biology, inheritance, clinical presentation, diagnostic strategies, and management principles across age groups. Participants will learn to recognize triggers, interpret laboratory findings, and implement evidence-based interventions for hemolysis and hyperbilirubinemia, and gain strategies for interprofessional coordination. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying the G6PD, performing the recommended evaluation, and implementing an appropriate interprofessional approach when managing this condition, ultimately optimizing patient-centered care, medication safety, and long-term outcomes through proactive education, testing, and prevention.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 8 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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