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StatPearls, LLC

  • Hypergammaglobulinemia
  • Monoclonal Gammopathy of Undetermined Significance

Hypergammaglobulinemia (Polyclonal Gammopathy)

Hypergammaglobulinemia (polyclonal gammopathy)’ refers to the overproduction of more than one class of immunoglobulins by plasma cells. It is most commonly associated with liver disease, acute or chronic inflammation, autoimmune disorders, and some malignancies. Hypergammaglobulinemia (polyclonal gammopathy) is generally considered a benign condition that does not progress to overt malignancy, contrary to monoclonal gammopathy of undetermined significance (MGUS). This activity outlines the evaluation and management of ‘hypergammaglobulinemia (polyclonal gammopathy)’ and highlights the role of the inter-professional team in evaluating and treating patients with this condition.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1 creditAMA PRA Category 1 Credit™Up to 1 creditNursingUp to 1 creditPharmacyUp to 1 credit

MOC types

ABS — Accredited CMEUp to 1 pointABPATH — Lifelong LearningUp to 1 pointABTS — Accredited CMEUp to 1 pointABIM — Medical KnowledgeUp to 1 pointABS — Self-AssessmentUp to 1 pointABTS — Self-AssessmentUp to 1 point

FDA REMS

No

Qualifies for MIPS

No

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1 credit
  • MOC · Up to 1 point
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left