StatPearls, LLC

  • Citric Acid
  • Flavin Mononucleotide
  • Riboflavin
  • Riboflavin Deficiency
  • Vitamin B Complex

Riboflavin Deficiency

Riboflavin (vitamin B2) is a water-soluble, heat-stable vitamin essential for cellular energy metabolism. It serves as a precursor to flavin adenine dinucleotide and flavin mononucleotide, cofactors required for flavoproteins involved in the citric acid cycle, mitochondrial electron transport, redox reactions, and metabolism of other B vitamins. These processes support ATP production and cellular homeostasis. Riboflavin also has antioxidant functions and supports immune health as well as skin and mucosal integrity. Deficiency may cause mucocutaneous lesions, normocytic anemia, fatigue, and neuromuscular symptoms, and can lead to secondary niacin deficiency. At-risk populations include those with poor intake, malabsorption, chronic alcohol use, or genetic disorders affecting riboflavin metabolism. Evaluation includes clinical assessment and measurement of erythrocyte glutathione reductase activation coefficient. Management involves dietary optimization, supplementation, and interprofessional care to prevent complications and improve outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 2 creditsAAPA Category 1 Credit™Up to 2 creditsAMA PRA Category 1 Credit™Up to 2 creditsNursingUp to 2 creditsPharmacyUp to 2 credits

MOC types

ABS — Accredited CMEUp to 2 pointsABPATH — Lifelong LearningUp to 2 pointsABTS — Accredited CMEUp to 2 pointsABIM — Medical KnowledgeUp to 2 pointsABS — Self-AssessmentUp to 2 pointsABP — Lifelong Learning and Self-AssessmentUp to 2 pointsABTS — Self-AssessmentUp to 2 points

FDA REMS

No

Qualifies for MIPS

No

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 2 credits
  • MOC · Up to 2 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left