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StatPearls, LLC

  • Gastrins
  • Gastritis, Atrophic
  • Neoplasm Metastasis
  • Neuroendocrine Tumors
  • Zollinger-Ellison Syndrome

Gastric Neuroendocrine Tumors

Gastric neuroendocrine tumors (GNETs) are rare neoplasms arising from enterochromaffin-like cells in the gastric mucosa, accounting for less than 1% of all gastric tumors. Their increasing detection is attributed to the widespread use of upper endoscopy. GNETs are classified into 3 main subtypes: Type 1, Type 2, and Type 3, each with distinct pathophysiology and clinical behavior. Type 1 GNETs, the most common, develop in the setting of chronic atrophic gastritis and hypergastrinemia, typically presenting as small, multifocal tumors with a low risk of metastasis. Type 2 GNETs are associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type 1 (MEN1), exhibiting variable malignancy potential. Type 3 GNETs, in contrast, are sporadic, gastrin-independent, and more aggressive, often presenting as solitary, large tumors with a high risk of metastasis. GNETs exhibit variable clinical courses, ranging from indolent, localized tumors to highly malignant forms with metastatic potential. This course explores the complexities surrounding diagnosis and management, which vary based on tumor type, size, grade, and metastatic risk. Given their heterogeneous nature, GNETs necessitate an interprofessional approach for optimal diagnosis, treatment, and long-term surveillance. This activity is designed for healthcare professionals to enhance their competence in recognizing the clinical features and classification of GNETs, performing the recommended evaluation, and implementing an appropriate interprofessional management approach to improve patient outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 2 creditsAMA PRA Category 1 Credit™Up to 2 creditsNursingUp to 2 creditsPharmacyUp to 2 credits

MOC types

ABS — Accredited CMEUp to 2 pointsABPATH — Lifelong LearningUp to 2 pointsABA — Lifelong LearningUp to 2 pointsABTS — Accredited CMEUp to 2 pointsABIM — Medical KnowledgeUp to 2 pointsABS — Self-AssessmentUp to 2 pointsABP — Lifelong Learning and Self-AssessmentUp to 2 pointsABTS — Self-AssessmentUp to 2 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 2 credits
  • MOC · Up to 2 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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