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StatPearls, LLC

  • Confusion
  • Hyperinsulinism
  • Hypoglycemia
  • Insulin
  • Insulinoma

Insulinoma

Insulinoma is a rare functional neuroendocrine tumor arising from pancreatic islet cells. Most cases are sporadic, although some are linked to multiple endocrine neoplasia type 1 (MEN1) syndrome. These tumors secrete excessive insulin, leading to hyperinsulinemia and hypoglycemic episodes, especially during fasting. Symptoms include fasting hypoglycemia, palpitations, tremors, and neuroglycopenic effects like confusion and seizures. Diagnosis involves demonstrating inappropriate hyperinsulinemia during hypoglycemia, supported by imaging studies. Most insulinomas are benign and treated with surgical resection, which is often curative. For inoperable cases, medical management helps control hypoglycemia. Metastatic disease may require debulking surgery, locoregional therapies, or liver-directed interventions like embolization or ablation. The prognosis depends on tumor size, metastatic spread, and genetic factors. This activity for healthcare professionals is designed to enhance the learner’s competence in recognizing the clinical manifestations of insulinoma, performing the recommended evaluation, and implementing an appropriate interprofessional management approach to improve patient outcomes.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

AAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 9 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left

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