StatPearls, LLC

  • Gastrinoma
  • Gastrins
  • Gastroesophageal Reflux
  • Multiple Endocrine Neoplasia Type 1
  • Zollinger-Ellison Syndrome

Gastrinoma

Gastrinoma is a functional neuroendocrine tumor that autonomously secretes gastrin, leading to excessive gastric acid production and the development of Zollinger-Ellison syndrome (ZES). ZES manifests with refractory peptic ulcer disease, severe gastroesophageal reflux, and secretory diarrhea. Gastrinomas predominantly arise within the “gastrinoma triangle,” encompassing the pancreas and duodenum, and frequently occur in association with multiple endocrine neoplasia type 1 (MEN1). This course explores the complexities surrounding this condition, including the current diagnostic challenges and elusive pathophysiology. Notably, metastatic dissemination is evident in approximately 60% of patients at diagnosis, emphasizing the imperative for early and accurate detection to enable prompt therapeutic intervention, reduce further metastatic spread, and ultimately improve patient prognosis. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying a gastrinoma, performing the recommended evaluation and long-term surveillance, and implementing an appropriate interprofessional approach when managing this condition to optimize patient care.

Credit & MOC Details

Credit information is provided by the course provider. We recommend confirming credit eligibility with the provider or your licensing board before starting the activity.

Credit types

IPCE CreditsUp to 1.5 creditsAAPA Category 1 Credit™Up to 1.5 creditsAMA PRA Category 1 Credit™Up to 1.5 creditsNursingUp to 1.5 creditsPharmacyUp to 1.5 credits

MOC types

ABS — Accredited CMEUp to 1.5 pointsABPATH — Lifelong LearningUp to 1.5 pointsABA — Lifelong LearningUp to 1.5 pointsABTS — Accredited CMEUp to 1.5 pointsABIM — Medical KnowledgeUp to 1.5 pointsABS — Self-AssessmentUp to 1.5 pointsABP — Lifelong Learning and Self-AssessmentUp to 1.5 pointsABTS — Self-AssessmentUp to 1.5 points

FDA REMS

No

Qualifies for MIPS

No

Target Specialties

Cross-Specialty

Relevant across 10 specialties.

Pricing

Fee varies

This provider typically $49–98

See fees on statpearls.com

Listed by the provider

  • Article / monograph / reference
  • Credit · Up to 1.5 credits
  • MOC · Up to 1.5 points
  • Fee varies · this provider typically $49–98
  • Released
    Sep 1, 2026
  • Last day to claim credit
    Sep 1, 2029 3 years left